Paracetamol allergy: how to recognize it and what to do

paracetamol allergy
Irina Makarova
Author allergist
Irina Makarova
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What is paracetamol?

Paracetamol, also known as acetaminophen, is one of the most popular anti-pain and antipyretic drugs in the world. Its reliability and effectiveness has been proven by decades of practical use.

History and use of paracetamol

Paracetamol was first synthesized in 1878, but its widespread use did not begin until the middle of the 20th century. The drug is used to reduce pain syndrome of various origins and control fever. It can be used both alone and as part of a combination remedy.

The mechanism of action of paracetamol

Paracetamol acts by reducing the synthesis of prostaglandins - substances involved in the transmission of pain impulses and the formation of the body's heat response. However, despite its effectiveness, some people may develop an allergy to paracetamol.

Symptoms of allergy to paracetamol

symptoms of paracetamol allergy

An allergic reaction to paracetamol can manifest itself in different ways. Common symptoms include skin rash, itching, swelling of the face or lips, as well as more serious manifestations, up to and including anaphylactic shock.

Diagnosis of paracetamol allergy

Skin tests and blood tests for specific antibodies are used to determine a paracetamol allergy. If such an allergy is suspected, the doctor may decide to perform provocation tests, but they should only be performed under strict medical supervision.

Treatment of paracetamol allergy

paracetamol allergy treatment

If the diagnosis is confirmed, it is important to stop taking the drug immediately.

If signs of allergy to paracetamol occur, an antihistamine such as Suprastin or Tavegil should be taken.

Antihistamines help reduce the severity of allergy symptoms such as itching and swelling. Modern antihistamines include Cetrin, Erius, and Zyrtec.

If you have a confirmed allergy to paracetamol, it is important to eliminate its intake in the future and find alternative means of pain relief and antipyretic. Your doctor may recommend other drugs, such as ibuprofen or aspirin, if you have no contraindications for taking them.

Preventing paracetamol allergies

Preventing allergies to paracetamol is about avoiding taking it. If you have had an allergic reaction to this drug in the past, it is important to tell your doctor. In addition, it is advisable to always read the composition of the drugs carefully, since paracetamol can be one of the components.

In conclusion, it should be emphasized that allergies to paracetamol, although rare, can be a serious problem. No matter what medication you take, always monitor your body's reaction and consult your doctor at the first sign of allergy.


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